Liposarcoma Directory

Phase II Study of Troglitazone as Antineoplastic Differentiation Therapy in Patients With Malignant Liposarcoma
	OBJECTIVES:I. Evaluate the clinical activity of troglitazone in patients with malignant liposarcoma.II. Evaluate the tolerance and safety of troglitazone in this patient population.PROTOCOL OUTLINE:This is an open label trial.All patients are given ...

Phase II Study of Rosiglitazone in Patients With Liposarcoma
	OBJECTIVES: I. Determine the clinical activity of rosiglitazone in patients with liposarcoma.II. Assess the impact of this regimen on markers of tumor proliferation and differentiation status in these patients using biologic and biochemical testing ...

A Randomized Multicenter Open-Label Study of YONDELIS ET-743 (Ecteinascidin) Administered by Two Different Schedules (Weekly for 3 of 4 Weeks Vs. q3 Weeks) in Subjects With Locally Advanced or Metasta
	This is a study to test the safety and effectiveness of an investigational chemotherapy agent in subjects with advanced liposarcoma or leiomyosarcoma. Subjects who meet all entry criteria and have signed the informed consent will be enrolled in the ...

Phase I/II Study of Nelfinavir in Liposarcoma
	OBJECTIVES:- Determine the maximum tolerated dose of nelfinavir mesylate in patients with recurrent metastatic or unresectable liposarcoma. (Phase I)- Determine the pharmacokinetics of this drug in these patients. (Phase I)- Determine the response ...